Dr. Selcuk Kucukseymen

• Interventional Cardiology (Balloon and placing stents in clogged vessels and catheter-based treatment of structural heart diseases)
• Coronary artery disease
• Cardio-Oncology - Cardiotoxicity
• Valvular heart disease
• Hypertension
• Heart failure
• Cardiomyopathy
• High blood cholesterol (Dyslipidemia)
• Peripheral vascular disease
• Interpreting advanced imaging modalities of the heart (Cardiac MRI and Coronary CT)

He has authored over 80 original scientific articles and 3 book chapters regarding this expertise

• Grant Award for clinical fellowship from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) 2021
• Early Career Investigator Award from the American Heart Association (AHA) 2019
• Finalist for the Physician of the Year in Turkey (DoktorClub - Turkey’s Healthcare Awards) 2021
• Gold Star Reviewer Awards from the Journal of Cardiovascular Magnetic Resonance (JCMR) (IF 7.4) 2018

• Kucukseymen S, Ciatti F, Ciardetti N, Mattesini A, Di Mario C. Update on NIRS/IVUS: The Fundamental Aspects and Current Clinical Roles. Cardiac Interventions Today, 2022;16(3):41-48
• Nakamori S, Kucukseymen S, Rodriguez J, Yazdanian F, Ngo L, Gopal D, Manning W, Nezafat R. Obesity-Related Differences in Pathomechanism and Outcomes in Patients with HFpEF: A Cardiovascular Magnetic Resonance Study. JACC: Adv 2023 JADV033023-0210-T, Accepted
• Di Mario C, Kucukseymen S. Second generation drug-eluting stent: The longer, the better? Catheter Cardiovasc Interv. 2022:100(2);188-9
• Kucukseymen S, Iannaccone M, Grantham JA, Juricic S, Ciardetti N, Mattesini A, Strauss BH, Stojkovic S, Wijeysundera HC, Spertus JA, Werner GS, D'Ascenzo F, Di Mario C. Impact of successful percutaneous revascularization of chronic total occlusions on quality of life: a meta-analysis of 1803 patients in randomized and observational trials. JAMA 2023 Accepted article.
• Morales MA, Cirillo J, Nakata K, Kucukseymen S, Ngo LH, Izquierdo-Gardia D, Catana C, Nezafat R. Comparison of DeepStrain and Feature Tracking for Cardiac MRI Strain Analysis. J Magn Reson Imaging. 2022 Jul 28. doi: 10.1002/jmri.28374.
• Kucukseymen S, Yavin H, Barkagan M, Jang J, Shapira-Daniels A, Rodriguez J, Shim D, Pashakhanloo F, Pierce P, Manning WJ, Anter A, Nezafat R. Discordance in Scar Detection Between Electroanatomical Mapping and Cardiac MRI in an Infarct Swine Model. JACC Clin Electrophysiol. 2020;6(11):1452-1464.
• Guo R, Qi H, Amyar A, Cai X, Kucukseymen S, Haji-Valizadeh H, Rodriguez J, Paskavitz A, Pierce P, God du B, Thompson RB, Nezafat R. Quantification of changes in myocardial T1 * values with exercise cardiac MRI using a free-breathing non-electrocardiograph radial imaging. Magn Reson Med. 2022;88(4):1720-1733.
• Kucukseymen S, Ciardetti N, Stolcova M, Di Mario C, Meucci F. Platypnea Orthedoxia Syndrome following TAVI. Anatol J Cardiol. 2023, AJC-2023-172
• Kucukseymen S, Arafati A, Al-Otaibi T, El-Rewaidy H, Fahmy AS, Ngo LH, Nezafat R. Noncontrast Cardiac Magnetic Resonance Imaging Predictors of Heart Failure Hospitalization in Heart Failure with Preserved Ejection Fraction. J Magn Reson Imaging. 2022;55(6):1812-1825.
• Haji-Valizadeh H, Guo R, Kucukseymen S, Paskavitz A, Cai X, Rodriguez J, Pierce P, Goddu B, Kim D, Manning WJ, Nezafat R. Highly Accelerated Free-Breathing Real-time Phase Contrast Cardiovascular MRI via Complex-Difference Deep Learning. Magn Reson Med. 2021;86(2):804-819.
• Guo R, Cai X, Kucukseymen S, Rodriguez J, Paskavitz A, Pierce P, Goddu B, Thompson RB, Nezafat R. Free-breathing simultaneous myocardial T1 and T2 mapping with whole left ventricle coverage. Magn Reson Med. 2020 Oct 20. doi: 10.1002/mrm.28506.
• Kucukseymen S, Neisius U, Connie T, Manning WJ, Nezafat R. Negative Synergism of Diabetes Mellitus and Obesity on the Myocardium in Patients with Heart Failure with Preserved Ejection Fraction: A Cardiovascular Magnetic Resonance Study. Int J Cardiovasc Imaging. 2020;36(10):2027-38.
• El-Rewaidy H, Fahmy AS, Pashakhanloo F, Cai X, Kucukseymen S, Csecs I, Neisius U, Haji-Valizadeh H, Menze B, Nezafat R. Multi-domain convolutional neural network (MD-CNN) for radial reconstruction of dynamic cardiac MRI. Magn Reson Med. 2021;85(3):1195-1208.
• Jang J, Ngo LH, Mancio J, Kucukseymen S, Rodriguez J, Pierce P, Goddu B, Manning WJ, Nezafat R. Reproducibility of Myocardial Radiomic Features in Cardiac MRI Imaging. Radiol Cardiothorac Imaging. 2020;2(3):e190216.
• Guo R, Cai X, Kucukseymen S, Rodriguez J, Paskavitz A, Pierce P, Goddu B, Nezafat R. Free-breathing whole-heart multi-slice myocardial T1 mapping in 2 minutes. Magn Reson Med. 2021;85(6):3189-3199.
• Haji-Valizadeh H, Guo R, Kucukseymen S, Tuyen Y, Rodriguez J, Paskavotiz A, Pierce P, Goddu B, Ngo LH, Nezafat R. Comparison of Complex k-space Data and Magnitude-only for Training of Deep Learning-Based Artifact Suppression for Real-time Cine MRI. Front. Phys. 2021;9: 684184.
• Haji-Valizadeh H, Guo R, Kucukseymen S, Cai X, Rodriguez J, Pierce P, Goddu B, Manning WJ, Nezafat R. Artifact Reduction in Free-breathing, Free-Running Myocardial Perfusion Imaging with Interleaved Non-Selective RF Excitations. Magn Reson Med. 2021;86(2):954-963.
• Neisius U, El-Rewaidy H, Kucukseymen S, Tsao CW, Mancio J, Nakamori S, Manning WJ, Nezafat R. Texture Signatures of Native Myocardial T1 as Novel Imaging Markers for Identification of Hypertrophic Cardiomyopathy Patients without Scar. J Magn Reson Imaging. 2020;52(3):906-919.
• Kucukseymen S, Cekin AH, Bayar N, Arslan S, Uygur Kucukseymen E, Mercan T, Ozdemir S. A novel biomarker for prediction of atrial fibrillation susceptibility in patients with celiac disease. PLoS One. 2018;13(1):e0190382. doi: 10.1371/journal.pone.0190382.
• El-Rewaidy H, Neisius U, Mancio J, Kucukseymen S, Rodriguez J, Paskavitz A, Menze B, Nezafat R. Deep complex convolutional network for fast reconstruction of 3D late gadolinium enhancement cardiac MRI. NMR Biomed. 2020 Jul;33(7):e4312.
• Nezafat M, El-Rewaidy H, Kucukseymen S, Hauser TH, Fahmy AS. Deep convolution neural networks based artifact suppression in under-sampled radial acquisitions of myocardial T1 mapping images. Physics in Medicine & Biology, 2020;65(22): 225024. doi: 10.1088/1361-6560/abc04f.
• Kucukseymen S. Inflammation Effects on Stent Restenosis. Angiology. 2017 Jan 1:3319717701659.
• Sahinturk Y, Kucukseymen S, Avci R, Akarsu A, Yolcular BO, Koker G, Tokuc A, Bayar N, Arslan S. Visceral fat index: a novel predictor for coronary collateral circulation. Arch Endocrinol Metab. 2020;64(2):150-158.
• Bayar N, Yuksel IO, Kucukseymen S, Arslan S. Unexpected complication during transcatheter aortic valve replacement: Balloon that cannot inflate! Anatol J Cardiol. 2018;19(5):351-353.
• Kucukseymen S, Yuksel IO, Cagirci G, Koklu E, Karakus V, Cay S, Kus G, Kurtoglu E, Arslan S. Heart rate recovery as a novel test for predicting cardiac involvement in beta-thalassemia major. Acta Cardiol Sin 2017;33:410-419.
• Kucuk M, Celen MC, Yamasan BE, Kucukseymen S, Ozdemir S. “Effects of prasugrel on membrane potential and contractile activity of rat ventricular myocytes.” Pharmacol Rep. 2017;70(1):156-160.
• Bayar N, Guven R, Erkal Z, Akyol KC, Edebali MI, Kucukseymen S, Arslan S. Assessment of the association between the personality traits of young patients with acute coronary syndrome and the severity of coronary artery disease. Turk Kardiyol Dern Ars. 2017 Sep;45(6):514-519.
• Cagirci G, Kucukseymen S, Yuksel IO, Bayar N, Koklu E, Guven R, Arslan S. Relationship between vitamin D and coronary artery ectasia in subjects with normal CRP level. Korean Circ J 2017;47(2):231-237.
• Yuksel IO, Arslan S, Cagirci G, Koklu E, Ureyen CM, Bayar N, Kucukseymen S, Kus G, Guven R. Assessment of left ventricular function with tissue Doppler echocardiography and of B-type natriuretic peptide levels in patients undergoing transcatheter aortic valve implantation. Rev Port Cardiol. 2017 May;36(5):377-383.
• Kucukseymen S, Cagirci G, Bayar N, Yuksel IO, Koklu E, Arslan S. Which Came First, the Chicken or the Egg? Paradox in Peripheral Arterial Diseases. Angiology. 2017 Jan 1:3319717709176. doi: 10.1177/0003319717709176.
• Koklu E, Arslan S, Yuksel IO, Bayar N, Yilmaz GM, Kucukseymen S. Management of left ventricle free wall rupture developing due to acute myocardial infarction. Journal of Acute Medicine 7(1): 33-36, 2017.
• Kucukseymen S, Yuksel IO, Arslan S. C-reactive protein is the origin for novel biomarkers. Angiology. 2016 Jan 1:3319716685483.
• Yuksel IO, Cagirci G, Koklu E, Yilmaz A, Kucukseymen S, Ellidag HY, Cay S, Yilmaz N, Arslan S. Erythropoietin stimulates the coronary collateral development in patients with coronary chronic total occlusion. Neth Heart J. 2016 Oct;24(10):609-16.
• Yuksel IO, Akar Bayram N, Koklu E, Ureyen CM, Kucukseymen S, Arslan S, Bozkurt E. Assessment of Impact of Weight Loss on Left and Right Ventricular Functions and Value of Tissue Doppler Echocardiography in Obese Patients. Echocardiography. 2016 Jun;33(6):854-61.
• Ellidag HY, Aydin O, Eren E, Yilmaz N, Gencpinar T, Kucukseymen S, Yilmaz A, Arslan Ince FD. Phenotype distribution of the paraoxonase gene in patients with cardiac disease. Arch Med Sci 2017;13(4):820–826.
• Kucukseymen S, Erkal Z, Bayar N, Arslan S. A Case of Left Main Coronary Thrombosis Treated Using Tirofiban. Cyprus J Med Sci 2017; 2: 35-7 Doi:10.5152/cjms.2016.161.
• Erkal Z, Bayar N, Esin M, Kucukseymen S, Guven R, Arslan S. Predictive Value of Fragmented QRS in Response to Levosimendan Therapy in Patients with Heart Failure. Cyprus J Med Sci 2016; 1: 42-5.
• Kucukseymen S, Cagirci G, Bayar N, Arslan S. Vitamin D trials and their limitations. Angiology. 2016:3319716683494.
• Yuksel IÖ, Koklu E, Arslan S, Cagirci G, Kucukseymen S. Aortic embolization of an Edwards SAPIEN prosthesis due to sigmoid left ventricular hypertrophy: Case report. Rev Port Cardiol. 2016 Jun;35(6):379.e1-3.
• Yilmaz A, Yilmaz B, Kucukseymen S, Ozpelit E, Pekel N. Association of overhydration and cardiac dysfunction in patients have chronic kidney disease but not yet dialysis. Nephrol Ther. 2016;12(2:94-7.
• Yuksel IO, Koklu E, Kurtoglu E, Arslan S, Cagirci G, Karakus V, Kus G, Cay S, Kucukseymen S. The Association between Serum Ferritin Level, Tissue Doppler Echocardiography, Cardiac T2* MRI, and Heart Rate Recovery in Patients with Beta Thalassemia Major. Acta Cardiol Sin. 2016 Mar;32(2):231-8.
• Bayar N, Kucukseymen S, Guven R, Erkal Z, Koklu E, ̇Yuksel IO, Cagirci G, Arslan S. Association between serum uric acid and ischemic stroke in patients with nonvalvular paroxysmal atrial fibrillation. (2016) doi: 10.1016/j.ijc ac.2016.09.003.
• Koklu E, Yuksel IO, Arslan S, Bayar N, Koklu F, Cay S, Cagirci G, Kucukseymen S, Kus G. Short and Long-Term Effect of Carotid Artery Stenting on Arterial Blood Pressure Measured through Ambulatory Blood Pressure M onitoring. Acta Cardiol Sin. 2016;32(3):343-50.
• Bayar N, Cekin AH, Ars lan S, Cagirci G, Kucukseymen S, Cay S, Harmandar FA, Yesil B. Assessment of Aortic Elasticity in Patients with Celiac Disease. Korean Circ J. 2016;46(2):239-45.
• Yilmaz A, Yilmaz B, Kucukseymen S. ß-2 microglobulin level is negatively associated with global left ventricular longitudinal peak systolic strain and left atrial volume index in patients with chronic kidney disease not on dialysis. Anatol J Cardiol. 2016 Nov;16(11):844-849.
• Bayar N, Kus G, Kucukseymen S, Koklu E, Arslan S. A rare cause of myocardial infarctıon: Vegetatıon embolism. (2016) doi: 10.1016/j.ijcac.2016.08.002.
• Bayar N, Ureyen CM, Erkal Z, Kucukseymen S, Cay S, Cagirci G, Arslan S. Evaluation of the association between stroke/transient ischemic attack and atrial electromechanical delay in patients with paroxysmal atrial fibrillation. Anatol J Cardiol. 2016 Aug;16(8):572-578.
• Yuksel İÖ, Koklu E, Arslan S, Ureyen CM, Kucukseymen S. Aortopulmonary window in adulthood: Surviving at 22 years without intervention or pulmonary vascular disease. Turk Kardiyol Dern Ars. 2016;44(4):332-4.
• Yuksel IO, Koklu E, Arslan S, Cagirci G, Kucukseymen S. Proximal embolization of Edwards SAPIEN prosthesis in transcatheter aortic valve implantation. Turk Kardiyol Dern Ars. 2016;44:75-8.
• Bayar N, Kucukseymen S, Erkal Z, Guven R, Koklu E, Ureyen CM, Arslan S. Relationship between mean platelet volume and ischemic stroke in patients with patent foramen ovale. Turk Kardiyol Dern Ars. 2017;45(1):9-15.
• Bayar N, Cekin AH, Arslan S, Cagirci G, Erkal Z, Cay S, Koklu E, Kucukseymen S. Assessment of Left Atrial Function in Patients with Celiac Disease. Echocardiography. 2015;32(12):1802-8.
• Kucukseymen S, Cagirci G, Oner Yuksel I, Bayar N, Koklu E, Cagin Ureyen M, Arslan S. Very late drug-eluting stent thrombosis with bare-metal stent simultaneously after excessive alcohol intake despite dual antiplatelet therapy after 2737 days. Minerva Cardioangiol. 2015;63(2):161-3.
• Bayar N, Arslan S, Cagirci G, Ureyen CM, Cay S, Yuksel IO, Koklu E, Erkal Z, Kucukseymen S. Usefulness of mean platelet volume for predicting stroke risk in paroxysmal atrial fibrillation patients. Blood Coagul Fibrinolysis. 2015 Sep;26(6):669-72. doi: 10.1097/MBC.0000000000000334.
• Kucukseymen S, Cagirci G, Koklu E, Yuksel IO, Bayar N, Esin M, Arslan S. Acute hemolysis in glucose-6-phosphate dehydrogenase deficiency after coronary angiography. Gazzetta medica italiana 2015;174(9):427-30.
• Koklu E, Kus G, Yuksel IO, Kucukseymen S, Arslan S. Successful thrombolytic therapy for ST-elevation acute myocardial infarction in a patient with immune thrombocytopenic purpura. Am J Emerg Med. 2015 Jun 19. pii: S0735-6757(15)00504-5.
• Bayar N, Arslan S, Cagirci G, Erkal Z, Ureyen CM, Cay S, Koklu E, Yuksel IO, Kucukseymen S. Assessment of morphology of patent foramen ovale with transesophageal echocardiography in symptomatic and asymptomatic patients. J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1282-6.
• Bayar N, Arslan S, Koklu E, Cagirci G, Cay S, Erkal Z, Ayoglu RU, Kucukseymen S. The importance of electrocardiographic findings in the diagnosis of atrial septal defect. Kardiol Pol. 2015;73(5):331-6.
• Koklu E, Yuksel IO, Bayar N, Kucukseymen S, Arslan S. Subarachnoid hemorrhage that electrocardiographically mimics acute coronary syndrome: a case report. Turk Kardiyol Dern Ars. 2015 Dec;43(8):730-3.
• Arslan S, Yuksel IO, Koklu E, Cagirci G, Ureyen CM, Bayar N, Kucukseymen S, Kus G. Clinical and morphological features of patients who underwent endovascular interventions for lower extremity arterial occlusive diseases. Postepy Kardiol Interwencyjnej. 2015;11(2):114-8.
• Yilmaz B, Yilmaz A, Sari F, Sarikaya AM, Ellidag HY, Kucukseymen S, Ozpelit E. Decrease of Urotensin II activity can impact on the volume status in predialysis Ren Fail. 2015 Apr;37(3):476-81.
• Eren E, Ellidag HY, Aydin O, Kucukseymen S, Giray O, Aslan S, Yilmaz N. The relationship between HDL-associated PON1 activity, oxidative stress and brain natriuretic peptide in NYHA functional class ii-i v heart failure patients. Biomedical Research 2015; 26 (3): 399-406.
• Yuksel IO, Koklu E, Cagirci, G, Kucukseymen S, Kus G, Arslan S. Successful percutaneous closure of a tortuous coronary artery to pulmonary artery fistula using the anchor technique: a different approach. Postepy Kardiol Interwencyjnej. 2015;11(4): 344-6.
• Koklu E, Yuksel IO, Bayar N, Kucukseymen S, Arslan S. Subarachnoid hemorrhage that electrocardiographically mimics acute coronary syndrome: a case report. Turk Kardiyol Dern Ars. 2015 Dec;43(8):730-3.
• Arslan S, Cagirci G, Bayar N, Koklu E, Yuksel IO, Kucukseymen S, Erkal Z, Ureyen CM, Gundogdu F, Gurlertop Y, Erol MK, Ceviz N. Corrected balloon occlusive diameter to determine device size during percutaneous atrial septal defect closure. Turk Kardiyol Dern Ars. 2015 Jul;43(5):420-6.
• Bayar N, Kucukseymen S, Goktas S, Arslan S. Right ventricle failure associated with trastuzumab. Therapeutic Advances in Drug Safety June 2015 6: 98-102.
• Bayar N, Kurtoglu E, Arslan S, Erkal Z, Cay S, Cagirci G, Deveci B, Kucukseymen S. Assessment of the relationship between fragmented QRS and cardiac iron overload in patients with beta-thalassemia major. Anatol J Cardiol. 2015 Feb;15(2):132-6.
• Bayar N, Arslan S, Koklu E, Cagirci G, Cay S, Erkal Z, Ayoglu RU, Kucukseymen S. The importance of electrocardiographic findings in the diagnosis of atrial septal defect. Kardiol Pol. 2015;73(5):331-6.
• Bayar N, Cagirci G, Ureyen CM, Kus G, Kucukseymen S, Arslan S. The Relationship between Spontaneous Multi-Vessel Coronary Artery Dissection and Celiac Disease. Korean Circ J. 2015;45(3):242-4.
• Koklu E, Yuksel IO, Erkal Z, Kucukseymen S, Arslan S. An unusual thrombolytic therapy decision in prosthetic valve thrombosis during early pregnancy. Turk Kardiyol Dern Ars. 2015;43(6):554-7.
• Bayar N, Kurtoglu E, Arslan S, Kucukseymen S. Author's Reply to Iron overload and fragmented QRS in patients with Thalassemia major: Mechanisms, therapies, and new horizons. Anatol J Cardiol. 2015;15(7):592-3.
• Erkal Z. Bayar N. Kucukseymen S. Cagirci G. Arslan S. Takotsubo Cardiomyopathy after Cholecystectomy Operation. MN Kardiyoloji 2015;22:37-39
• Bayar N, Arslan S, Cagirci G, Kucukseymen S. Extreme bradycardia associated with nebivolol therapy. Int J Cardiol. 2014;177(1):e29-31.
• Bayar N, Arslan S, Erkal Z, Kucukseymen S. Sustained ventricular tachycardia in a patient with thalassemia major. Ann Noninvasive Electrocardiol. 2014;19(2):193-7.
• Yuksel IO, Koklu E, Arslan S, Cagirci G, Kucukseymen S, Kus G. Endovascular Treatment of Iliac Artery Stenosis in Patients with Renal Transplant and Pelvic Ectopic Kidney: Rare Two Cases. Int J Cardiovasc Res 4:3. doi: 10.4172/2324-8602.1000210
• Yuksel IO, Kucukseymen S, Cagirci G, Arslan S. A case of percutaneous mitral balloon valvuloplasty complicated by pericardial effusion and thrombus formation on the interatrial septum. Turk Kardiyol Dern Ars. 2014;42(8):747-50.
• Bayar N. Arslan S. Yuksel IO. Yilmaz A. Kucukseymen S. “Honeycomb Appearance of the Coronary Artery: Chronic Dissection” MN Cardiol 2014;21:47-49
• Yuksel IO, Arslan S, Bayar N, Kucukseymen S, Koklu E, Erol B. An unusual pattern of all three coronary arteries originating from a single coronary artery arising from the right sinus of valsalva. Korean Circ J. 2014;44(2):125-7.
• Bayar N, Kucukseymen S, Yuksel IO, Arslan S. Rapidly improving acute myocarditis after a scorpion sting. Turk Kardiyol Dern Ars. 2013;41(7):629-32.
• Yuksel IO, Yilmaz GM, Koklu E, Bayar N, Kucukseymen S, Arslan S. Ventricular tachycardia and syncope: a complication of an echinococcal cyst caused by left ventricular outflow tract obstruction. Anatol J Cardiol. 2014; 15(1):E1-2.
• Bayar N. Arslan S. Erkal Z. Kucukseymen S. “Type 4 Left Anterior Descending Coronary Artery Overlooked Critical Stenosis: A Case Report” MN Cardiol 2013;20:206-208